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Article

Modelling allelic drop-outs in STR sequencing data generated by MPS.

Forensic science international. Genetics - 1 Nov 2018

Vilsen Søren B, Tvedebrink Torben, Eriksen Poul S, Hussing Christian, Børsting Claus, Morling Niels

Abstract excerpt

We used a Poisson-gamma model to analyse the allele coverage of autosomal short tandem repeat (STR) systems obtained by massively parallel sequencing (MPS). The Poisson-gamma coverage model was created using the peak height models from capillary electrophoresis (CE) based detection of PCR products as a starting point. The CE models were modified to account for the differences between CE and MPS signals by...

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PMID: 30071494
DOI: 10.1016/j.fsigen.2018.07.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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