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Article

Characterizing the activity of abundant, diverse and active CRISPR-Cas systems in lactobacilli.

Scientific reports - 1 Aug 2018

Crawley Alexandra B, Henriksen Emily D, Stout Emily, Brandt Katelyn, Barrangou Rodolphe

Abstract excerpt

CRISPR-Cas systems provide immunity against phages and plasmids in bacteria and archaea. Despite the popularity of CRISPR-Cas9 based genome editing, few endogenous systems have been characterized to date. Here, we sampled 1,262 publically available lactobacilli genomes found them to be enriched with CRISPR-Cas adaptive immunity. While CRISPR-Cas is ubiquitous in some Lactobacillus species, CRISPR-Cas content...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30068963
DOI: 10.1038/s41598-018-29746-3
PMCID: PMC6070500

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PAM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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