Article
Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium.
PloS one - 1 Jan 2015
Briner Alexandra E, Lugli Gabriele Andrea, Milani Christian, Duranti Sabrina, Turroni Francesca, Gueimonde Miguel, Margolles Abelardo, van Sinderen Douwe, Ventura Marco, Barrangou Rodolphe
Abstract excerpt
CRISPR-Cas systems constitute adaptive immune systems for antiviral defense in bacteria. We investigated the occurrence and diversity of CRISPR-Cas systems in 48 Bifidobacterium genomes to gain insights into the diversity and co-evolution of CRISPR-Cas systems within the genus and investigate CRISPR spacer content. We identified the elements necessary for the successful targeting and inference of foreign DNA in...
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