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Article

Childhood adversity and DNA methylation in two population-based cohorts

3 Dec 2018

Abstract excerpt

Childhood adversity affects later health, but the underlying molecular mechanisms are unclear. Although there is some evidence from animal models and case-control studies of a role for DNA methylation, evidence from human population-based studies is limited. In two cohorts (mothers from the Avon Longitudinal Study of Parents and Children, ALSPAC, n = 780 and women from the MRC National Survey of Health and...

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PMID: 30510187
DOI: 10.1038/s41398-018-0307-3

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