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Article

SCN5A mutations in 442 neonates and children: genotype–phenotype correlation and identification of higher-risk subgroups

3 Jul 2018

Abstract excerpt

Aims: To clarify the clinical characteristics and outcomes of children with SCN5A-mediated disease and to improve their risk stratification. Methods and results: A multicentre, international, retrospective cohort study was conducted in 25 tertiary hospitals in 13 countries between 1990 and 2015. All patients ≤16 years of age diagnosed with a genetically confirmed SCN5A mutation were included in the analysis....

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PMID: 30059973
DOI: 10.1093/eurheartj/ehy412

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