Article
The immunomodulatory activity of extracellular vesicles derived from endometrial mesenchymal stem cells on CD4+ T cells is partially mediated by TGFbeta.
Journal of tissue engineering and regenerative medicine - 1 Oct 2018
Álvarez Verónica, Sánchez-Margallo Francisco Miguel, Macías-García Beatriz, Gómez-Serrano María, Jorge Inmaculada, Vázquez Jesús, Blázquez Rebeca, Casado Javier G
Abstract excerpt
Endometrial mesenchymal stem cells (endMSCs) reside in the basal and functional layer of human endometrium and participate in tissue remodelling, which is required for maintaining the regenerative capacity of the endometrium. The endMSCs are multipotent stem cells and exhibit immunomodulatory effects. This paper aimed to evaluate the regulatory effects of extracellular vesicles derived from endMSCs (EV-endMSCs)...
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