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Article

Impact of serum cholesterol esterification rates on the development of diabetes mellitus in a general population.

Lipids in health and disease - 28 Jul 2018

Tanaka Shin-Ichiro, Fujioka Yoshio, Tsujino Takeshi, Ishida Tatsuro, Hirata Ken-Ichi

Abstract excerpt

BACKGROUND: Lecithin:cholesterol acyltransferase (LCAT) plays an important role in cholesterol esterification in serum. Serum LCAT activity is elevated in patients with serum high triglyceride and low high-density lipoprotein-cholesterol (HDL-C) concentrations, both of which are related to metabolic syndrome and subsequent diabetes mellitus, referred to as lipotoxicity. We hypothesized that increased serum LCAT...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30055622
DOI: 10.1186/s12944-018-0822-5
PMCID: PMC6064622

Genes

LCAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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