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Article

Current Status of Familial LCAT Deficiency in Japan.

Journal of atherosclerosis and thrombosis - 1 Jul 2021

Kuroda Masayuki, Bujo Hideaki, Yokote Koutaro, Murano Takeyoshi, Yamaguchi Takashi, Ogura Masatsune, Ikewaki Katsunori, Koseki Masahiro, Takeuchi Yasuo, Nakatsuka Atsuko, Hori Mika, Matsuki Kota, Miida Takashi, Yokoyama Shinji, Wada Jun, Harada-Shiba Mariko

Abstract excerpt

Lecithin cholesterol acyltransferase (LCAT) is a lipid-modification enzyme that catalyzes the transfer of the acyl chain from the second position of lecithin to the hydroxyl group of cholesterol (FC) on plasma lipoproteins to form cholesteryl acylester and lysolecithin. Familial LCAT deficiency is an intractable autosomal recessive disorder caused by inherited dysfunction of the LCAT enzyme. The disease appears...

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Identifiers

PMID: 33867422
DOI: 10.5551/jat.RV17051
PMCID: PMC8265425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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