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Article

A systematic review of the natural history and biomarkers of primary lecithin:cholesterol acyltransferase deficiency.

Journal of lipid research - 1 Mar 2022

Vitali Cecilia, Bajaj Archna, Nguyen Christina, Schnall Jill, Chen Jinbo, Stylianou Kostas, Rader Daniel J, Cuchel Marina

Abstract excerpt

Syndromes associated with LCAT deficiency, a rare autosomal recessive condition, include fish-eye disease (FED) and familial LCAT deficiency (FLD). FLD is more severe and characterized by early and progressive chronic kidney disease (CKD). No treatment is currently available for FLD, but novel therapeutics are under development. Furthermore, although biomarkers of LCAT deficiency have been identified, their...

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Identifiers

PMID: 35065092
DOI: 10.1016/j.jlr.2022.100169
PMCID: PMC8953693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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