Article
Low-Level Antimicrobials in the Medicinal Leech Select for Resistant Pathogens That Spread to Patients.
mBio - 24 Jul 2018
Beka Lidia, Fullmer Matthew S, Colston Sophie M, Nelson Michael C, Talagrand-Reboul Emilie, Walker Paul, Ford Bradley, Whitaker Iain S, Lamy Brigitte, Gogarten Johann Peter, Graf Joerg
Abstract excerpt
Fluoroquinolones (FQs) and ciprofloxacin (Cp) are important antimicrobials that pollute the environment in trace amounts. Although Cp has been recommended as prophylaxis for patients undergoing leech therapy to prevent infections by the leech gut symbiont Aeromonas, a puzzling rise in Cp-resistant (Cpr) Aeromonas infections has been reported. We report on the effects of subtherapeutic FQ concentrations on...
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