Article
Discovery of glycocholic acid and taurochenodeoxycholic acid as phenotypic biomarkers in cholangiocarcinoma.
Scientific reports - 23 Jul 2018
Song Won-Suk, Park Hae-Min, Ha Jung Min, Shin Sung Gyu, Park Han-Gyu, Kim Joonwon, Zhang Tianzi, Ahn Da-Hee, Kim Sung-Min, Yang Yung-Hun, Jeong Jae Hyun, Theberge Ashleigh B, Kim Byung-Gee, Lee Jong Kyun, Kim Yun-Gon
Abstract excerpt
Although several biomarkers can be used to distinguish cholangiocarcinoma (CCA) from healthy controls, differentiating the disease from benign biliary disease (BBD) or pancreatic cancer (PC) is a challenge. CCA biomarkers are associated with low specificity or have not been validated in relation to the biological effects of CCA. In this study, we quantitatively analyzed 15 biliary bile acids in CCA (n = 30), BBD...
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