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Article

Prognostic roles of tetrahydroxy bile acids in infantile intrahepatic cholestasis.

Journal of lipid research - 1 Mar 2017

Lee Chee-Seng, Kimura Akihiko, Wu Jia-Feng, Ni Yen-Hsuan, Hsu Hong-Yuan, Chang Mei-Hwei, Nittono Hiroshi, Chen Huey-Ling

Abstract excerpt

Tetrahydroxy bile acids (THBAs) are hydrophilic and are present at minimal or undetectable levels in healthy human adults, but are present at high levels in bile salt export pump (abcb11)-knockout mice. The roles of THBAs in human cholestatic diseases are unclear. We aimed to investigate the presence of THBAs in patients with infantile intrahepatic cholestasis and its correlation with outcome. Urinary bile acids...

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Share to Adenosine Triphosphatases
Share to ATP Binding Cassette Transporter, Subfamily B, Member 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Bile Acids and Salts

Share to Cholestasis, Intrahepatic

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Source

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Identifiers

PMID: 28073941
DOI: 10.1194/jlr.P070425
PMCID: PMC5335591

Genes

ABCB11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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