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Sub-Cellular Localization of Metalloproteinases in Megakaryocytes

20 Jul 2018

Abstract excerpt

Metalloproteinases (MMPs) are zinc-dependent endopeptidases that play essential roles as the mediator of matrix degradation and remodeling during organogenesis, wound healing and angiogenesis. Although MMPs were originally identified as matrixin proteases that act in the extracellular matrix, more recent research has identified members of the MMP family in unusual locations within the cells, exerting distinct...

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PMID: 30037039
DOI: 10.3390/cells7070080

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