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Article

Uptake of genetic testing by the children of Lynch syndrome variant carriers across three generations.

European journal of human genetics : EJHG - 1 Nov 2017

Seppälä Toni T, Pylvänäinen Kirsi, Mecklin Jukka-Pekka

Abstract excerpt

Many Lynch syndrome (LS) carriers remain unidentified, thus missing early cancer detection and prevention opportunities. Tested probands should inform their relatives about cancer risk and options for genetic counselling and predictive gene testing, but many fail to undergo testing. To assess predictive testing uptake and demographic factors influencing this decision in LS families, a cross-sectional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28832568
DOI: 10.1038/ejhg.2017.132
PMCID: PMC5643966

Genes

MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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