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The Myb-related protein MYPOP is a novel intrinsic host restriction factor of oncogenic human papillomaviruses

17 Jul 2018

Abstract excerpt

The skin represents a physical and chemical barrier against invading pathogens, which is additionally supported by restriction factors that provide intrinsic cellular immunity. These factors detect viruses to block their replication cycle. Here, we uncover the Myb-related transcription factor, partner of profilin (MYPOP) as a novel antiviral protein. It is highly expressed in the epithelium and binds to the minor...

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PMID: 30018400
DOI: 10.1038/s41388-018-0398-6

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