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Characterization of the accessible genome in the human malaria parasite Plasmodium falciparum

14 Jul 2018

Abstract excerpt

Human malaria is a devastating disease and a major cause of poverty in resource-limited countries. To develop and adapt within hosts Plasmodium falciparum undergoes drastic switches in gene expression. To identify regulatory regions in the parasite genome, we performed genome-wide profiling of chromatin accessibility in two culture-adapted isogenic subclones at four developmental stages during the...

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PMID: 30016465
DOI: 10.1093/nar/gky643

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