Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deficient primary cilia in obese adipose‐derived mesenchymal stem cells: obesity, a secondary ciliopathy?

17 Jul 2018

Abstract excerpt

Obesity alters the composition, structure and function of adipose tissue, characterized by chronic inflammation, insulin resistance and metabolic dysfunction. Adipose-derived mesenchymal stem cells (ASCs) are responsible for cell renewal, spontaneous repair and immunomodulation in adipose tissue. Increasing evidence highlights that ASCs are deficient in obesity, and the underlying mechanisms are not well...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic and Kidney Cyst Diseases
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30015415
DOI: 10.1111/obr.12716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deficient primary cilia in obese adipose‐derived mesenchymal stem cells: obesity, a secondary ciliopathy?PMID 30015415Read ↗

Peripheral and central control of obesity by primary ciliaSemantic proximity Read ↗

The role of primary cilia in obesity and diabetesSemantic proximity Read ↗

The cilium: a cellular antenna with an influence on obesity risk.Semantic proximity Read ↗

Ciliary dysfunction and obesity.Semantic proximity Read ↗

Alström syndrome: insights into the pathogenesis of metabolic disorders.Semantic proximity Read ↗

Cilia, Alström syndrome--molecular mechanisms and therapeutic perspectives.Semantic proximity Read ↗

Mechanisms of Weight Control by Primary CiliaSemantic proximity Read ↗

BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissueSemantic proximity Read ↗

Primary Cilium Is Involved in Stem Cell Differentiation and Renewal through the Regulation of Multiple Signaling PathwaysSemantic proximity Read ↗

Neuronal cilia in energy homeostasisSemantic proximity Read ↗

Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamusSemantic proximity Read ↗

A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.