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Extra-Chromosomal DNA Sequencing Reveals Episomal Prophages Capable of Impacting Virulence Factor Expression in Staphylococcus aureus

2 Jul 2018

Abstract excerpt

Staphylococcus aureus is a major human pathogen with well-characterized bacteriophage contributions to its virulence potential. Recently, we identified plasmidial and episomal prophages in S. aureus strains using an extra-chromosomal DNA isolation and sequencing approach, uncovering the plasmidial phage phiBU01, which was found to encode important virulence determinants. Here, we expanded our extra-chromosomal...

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PMID: 30013526
DOI: 10.3389/fmicb.2018.01406

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