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Plasma HPV cell-free DNA monitoring in advanced HPV-associated oropharyngeal cancer

13 Jul 2018

Abstract excerpt

Background: Measuring cell-free (cf)DNA in blood and tissues holds significant potential as a minimally invasive method for disease monitoring in cancer. Cancers arising in the oropharynx and causally linked to human papillomavirus (HPV) represent an ideal model in which to interrogate these methods. Patients and methods: We designed an ultrasensitive and quantitative droplet digital (dd)PCR assay to detect the...

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PMID: 30010779
DOI: 10.1093/annonc/mdy251

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