Article
HPV Serology and Circulating Viral DNA for Detection, Genotyping, and Measurement of Disease Burden in Oropharyngeal Cancer.
International journal of cancer - 1 Nov 2026
Penny Lucas, Stutheit-Zhao Eric Yang, Michels Birgitta E, Rosing Fabian, Zhao Zhen, Zheng Yangqiao, Zou Jinfeng, Huang Shao Hui, Carlton Johnny, McPartlin Andrew, de Almeida John R, Goldstein David, Hope Andrew, Hosni Ali, Kim John, Liu Fei-Fei, Tsai C Jillian, Waldron John N, Spreafico Anna, Sanz-Garcia Enrique, Siu Lillian L, Waterboer Tim, Liu Geoffrey, Bratman Scott V
Abstract excerpt
The incidence of human papillomavirus-positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost-effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to optimize early cancer detection. The potential for HPV circulating tumor...
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- Humans
- Oropharyngeal Neoplasms
- Papillomavirus Infections
- Female