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Circulating Cell-free DNA for Metastatic Cervical Cancer Detection, Genotyping, and Monitoring

12 Sept 2017

Abstract excerpt

Abstract Purpose: Circulating cell-free (ccf) human papillomavirus (HPV) DNA may serve as a unique tumor marker for HPV-associated malignancies, including cervical cancer. We developed a method to genotype and quantify circulating HPV DNA in patients with HPV16- or HPV18-positive metastatic cervical cancer for potential disease monitoring and treatment-related decision making. Experimental Design: In this...

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PMID: 28899967
DOI: 10.1158/1078-0432.ccr-17-1553

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