Article
Effectiveness and safety of 3 and 5 day courses of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar.
Malaria journal - 11 Jul 2018
Tun Kyaw Myo, Jeeyapant Atthanee, Myint Aung Hpone, Kyaw Zwe Thiha, Dhorda Mehul, Mukaka Mavuto, Cheah Phaik Yeong, Imwong Mallika, Hlaing Thaung, Kyaw Thar Htun, Ashley Elizabeth A, Dondorp Arjen, White Nicholas J, Day Nicholas P J, Smithuis Frank
Abstract excerpt
BACKGROUND: Artemisinin resistance in Plasmodium falciparum has emerged and spread in Southeast Asia. In areas where resistance is established longer courses of artemisinin-based combination therapy have improved cure rates. METHODS: The standard 3-day course of artemether-lumefantrine (AL) was compared with an extended 5-day regimen for the treatment of uncomplicated falciparum malaria in Kayin state in...
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