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Article

Influence of SIRT1 polymorphisms for diabetic foot susceptibility and severity.

Medicine - 1 Jul 2018

Peng Yi, Zhang Guishan, Tang Hongxia, Dong Luling, Gao Chunbin, Yang Xiuhong, Peng Ying, Xu Yanrong

Abstract excerpt

The present study aimed to explore the influence of sirtuin 1 (SIRT1) polymorphisms (rs12778366 and rs3758391) on diabetic foot (DF) susceptibility and severity in patients with type 2 diabetes mellitus (T2DM).This case-control study recruited 142 patients with DF, 148 patients with T2DM, and 148 healthy controls. SIRT1 gene polymorphisms were sequenced by polymerase chain reaction (PCR) and direct sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29995800
DOI: 10.1097/MD.0000000000011455
PMCID: PMC6076161

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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