Article

Metabolic Memory in Diabetic Foot Syndrome (DFS): Epigenetic Changes of the Expression of Micro-rnas and Single Nucleotide Polymorphisms (SNPS) Frequency in a Cohort of Diabetic Patients With and Without Foot Ulceration and Correlation With Indices of Endothelial and Adipo-inflammatory Dysfunction

2023-04-19

Abstract excerpt

Diabetic foot is a significant cause of morbidity in diabetic patients, with a rate that is approximately twice that of patients without foot ulcers. There has been much debate in the literature about the role of genetics, particularly epigenetic modifications, in the genesis of the diabetic foot. “Metabolic memory” are all those epigenetic changes induced by chronic hyperglycaemia, despite correction of the glyca...

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Literature Corpus work: f832f0c1-e24e-5391-8cb9-2c24b4cb581d
DOI: 10.21203/rs.3.rs-2814460/v1

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Metabolic Memory in Diabetic Foot Syndrome (DFS): Epigenetic Changes of the Expression of Micro-rnas and Single Nucleotide Polymorphisms (SNPS) Frequency in a Cohort of Diabetic Patients With and Without Foot Ulceration and Correlation With Indices of Endothelial and Adipo-inflammatory DysfunctionDOI 10.21203/rs.3.rs-2814460/v1Read

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