The high expression of FOXA1 is correlated with a favourable prognosis in salivary duct carcinomas: a study of 142 cases.

doi:10.1111/his.13706

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Article

The high expression of FOXA1 is correlated with a favourable prognosis in salivary duct carcinomas: a study of 142 cases.

Histopathology - 1 Dec 2018

Urano Makoto, Hirai Hideaki, Tada Yuichiro, Kawakita Daisuke, Shimura Tomotaka, Tsukahara Kiyoaki, Kano Satoshi, Ozawa Hiroyuki, Okami Kenji, Sato Yuichiro, Fushimi Chihiro, Shimizu Akira, Takase Soichiro, Okada Takuro, Sato Hiroki, Imanishi Yorihisa, Otsuka Kuninori, Watanabe Yoshihiro, Sakai Akihiro, Ebisumoto Koji, Togashi Takafumi, Ueki Yushi, Ota Hisayuki, Sato Yukiko, Saigusa Natsuki, Nakaguro Masato, Hanazawa Toyoyuki, Nagao Toshitaka

Abstract excerpt

AIMS: Salivary duct carcinoma (SDC) is an uncommon, aggressive tumour that, histologically, resembles high-grade mammary ductal carcinoma, and is characterised by the expression of androgen receptor (AR). The androgen signalling pathway, a potential therapeutic target, can be regulated by FOXA1. This study aimed to evaluate the clinicopathological implications of FOXA1 in SDC. METHODS AND RESULTS: We examined the...

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Identifiers

PMID: 29993139
DOI: 10.1111/his.13706

Genes

FOXA1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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