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Article

CYP3A5 and ABCB1 polymorphisms in living donors do not impact clinical outcome after kidney transplantation.

Pharmacogenomics - 1 Jul 2018

Yang Lin, de Winter Brenda Cm, van Schaik Ron Hn, Xie Rui-Xiang, Li Yi, Andrews Louise M, Shuker Nauras, Bahmany Soma, Koch Birgit, van Gelder Teun, Hesselink Dennis A

Abstract excerpt

AIM: To investigate the association between donor CYP3A5 and ABCB1 polymorphisms and tacrolimus (Tac)-induced nephrotoxicity and renal function in kidney transplant recipients. METHODS: The CYP3A5 6986A>G and ABCB1 3435C>T polymorphisms were determined in 237 recipients and donors. RESULTS: There was no significant association between Tac-related nephrotoxicity and donor CYP3A5 and ABCB1 genotype. The donor ABCB1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29991328
DOI: 10.2217/pgs-2018-0066

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CYP3A5 and ABCB1 polymorphisms in living donors do not impact clinical outcome after kidney transplantation.PMID 29991328Read ↗

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