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Article

PTPN22 profile indicates a novel risk group in Alopecia areata.

Human immunology - 1 Jan 2014

Bhanusali Dhaval G, Sachdev Amit, Olson Megan A, Gerlach John A, Sinha Animesh A

Abstract excerpt

Alopecia areata (AA) is a genetically determined autoimmune hair loss disorder. A polymorphism in protein tyrosine phosphatase N22 (PTPN22), which normally suppresses T-cell proliferation, has been associated with human autoimmune disease, including AA in European populations. PTPN22 genotype frequency in known to vary geographically. Accordingly, we conducted a case-control study of the PTPN22 1858C/1858T...

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Source

Identifiers

PMID: 24055692
DOI: 10.1016/j.humimm.2013.09.003

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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