Article
Essential thrombocythemia during treatment of acute myeloid leukemia with JAK2 V617F mutation: A case report of a CARE-compliant article.
Medicine - 1 Jul 2018
Ding Wenwen, Li Danni, Zhuang Chao, Wei Pingping, Mou Wenfeng, Zhang Lei, Liang Hui, Liu Yong
Abstract excerpt
RATIONALE: The JAK2 V617F mutation is frequently found in ET, while it is rare in de novo AML. ET has a low frequency of leukemic transformation. Both secondary AML (sAML) from ET and AML with JAK2 V617F mutation have poor prognoses. Because of the low incidence of JAK2 mutation in acute myeloid leukemia (AML), the clinical features of AML with JAK2 mutation are rarely reported so far, either transformed from...
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