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Article

LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs

5 Jul 2018

Abstract excerpt

BACKGROUND: Human Endogenous Retroviruses (HERVs) and Mammalian apparent LTR-retrotransposons (MaLRs) represent the 8% of our genome and are distributed among our 46 chromosomes. These LTR-retrotransposons are thought to be essentially silent except in cancer, autoimmunity and placental development. Their Long Terminal Repeats (LTRs) constitute putative promoter or polyA regulatory sequences. In this study, we...

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PMID: 29976163
DOI: 10.1186/s12864-018-4901-9

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