Article
Divergent and dynamic activity of endogenous retroviruses in burn patients and their inflammatory potential.
Experimental and molecular pathology - 1 Apr 2014
Lee Kang-Hoon, Rah HyungChul, Green Tajia, Lee Young-Kwan, Lim Debora, Nemzek Jean, Wahl Wendy, Greenhalgh David, Cho Kiho
Abstract excerpt
Genes constitute ~3% of the human genome, whereas human endogenous retroviruses (HERVs) represent ~8%. We examined post-burn HERV expression in patients' blood cells, and the inflammatory potentials of the burn-associated HERVs were evaluated. Buffy coat cells, collected at various time points from 11 patients, were screened for the expression of eight HERV families, and we identified their divergent expression...
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