Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MiR-137 Suppresses Triple-Negative Breast Cancer Stemness and Tumorigenesis by Perturbing BCL11A-DNMT1 Interaction

1 Jan 2018

Abstract excerpt

BACKGROUND/AIMS: Triple negative breast cancer (TNBC) is resistant to conventional chemotherapy due to high proportions of cancer stem cells (CSCs). The aim of this study is to unravel the miR-137-mediated regulatory mechanism of B-cell lymphoma/leukemia 11A (BCL11A) in TNBC. METHODS: A corhort of 34 TNBC tumor tissues and paired adjacent normal tissues, as well as 25 non-TNBC tumor tissues and paired adjacent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Circular RNAs in diseases
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29975921
DOI: 10.1159/000491526

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MiR-137 Suppresses Triple-Negative Breast Cancer Stemness and Tumorigenesis by Perturbing BCL11A-DNMT1 InteractionPMID 29975921Read ↗

BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cellsSemantic proximity Read ↗

BCL6 and the Notch pathway: a signaling axis leading to a novel druggable biotarget in triple negative breast cancerSemantic proximity Read ↗

A Novel Tumor Suppressor ASMTL-AS1 Regulates the Mir-1228-3p/SOX17/Β-Catenin Axis in Triple-Negative Breast CancerSemantic proximity Read ↗

MiR-4319 Suppress the Malignancy of Triple-Negative Breast Cancer by Regulating Self-Renewal and Tumorigenesis of Stem CellsSemantic proximity Read ↗

Cancer stem cell-derived CHI3L1 activates the MAF/CTLA4 signaling pathway to promote immune escape in triple-negative breast cancerSemantic proximity Read ↗

LncRNA Inhibits the Viability of Triple-Negative Breast Cancer (TNBC) by Targeting the miR-330-5p/BCL2L2 AxisSemantic proximity Read ↗

Signaling pathways essential for triple-negative breast cancer stem-like cellsSemantic proximity Read ↗

MicroRNA‑137 exerts protective effects on hypoxia‑induced cell injury by inhibiting autophagy/mitophagy and maintaining mitochondrial function in breast cancer stem‑like cellsSemantic proximity Read ↗

An Insight Into the Cancer Stem Cell Survival Pathways Involved in Chemoresistance in Triple-Negative Breast CancerSemantic proximity Read ↗

MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway.Semantic proximity Read ↗

YTHDF1 enhances stemness and chemoresistance in triple‐negative breast cancer cells by upregulating SIAH2Semantic proximity Read ↗

Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.