Article
Assessment of genetic factor and depression interactions for asthma symptom severity in cohorts of childhood and elderly asthmatics.
Experimental & molecular medicine - 4 Jul 2018
Park Heung-Woo, Song Woo-Jung, Cho Sang-Heon, McGeachie Michael J, Martinez Fernando, Mauger Dave, Bender Bruce G, Tantisira Kelan G
Abstract excerpt
It is well known that depression is associated with asthma symptoms. We assessed the combined effects of genetic factors and depression on asthma symptom severity using Bayesian network (BN) analysis. The common 100 top-ranked single-nucleotide polymorphisms (SNPs) were obtained from two genome-wide association studies of symptom severity in two childhood asthmatics trials (CAMP (Childhood Asthma Management...
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