Article
Stress and Bronchodilator Response in Children with Asthma.
American journal of respiratory and critical care medicine - 1 Jul 2015
Brehm John M, Ramratnam Sima K, Tse Sze Man, Croteau-Chonka Damien C, Pino-Yanes Maria, Rosas-Salazar Christian, Litonjua Augusto A, Raby Benjamin A, Boutaoui Nadia, Han Yueh-Ying, Chen Wei, Forno Erick, Marsland Anna L, Nugent Nicole R, Eng Celeste, Colón-Semidey Angel, Alvarez María, Acosta-Pérez Edna, Spear Melissa L, Martinez Fernando D, Avila Lydiana, Weiss Scott T, Soto-Quiros Manuel, Ober Carole, Nicolae Dan L, Barnes Kathleen C, Lemanske Robert F, Strunk Robert C, Liu Andrew, London Stephanie J, Gilliland Frank, Sleiman Patrick, March Michael, Hakonarson Hakon, Duan Qing Ling, Kolls Jay K, Fritz Gregory K, Hu Donglei, Fani Negar, Stevens Jennifer S, Almli Lynn M, Burchard Esteban G, Shin Jaemin, McQuaid Elizabeth L, Ressler Kerry, Canino Glorisa, Celedón Juan C
Abstract excerpt
RATIONALE: Stress is associated with asthma morbidity in Puerto Ricans (PRs), who have reduced bronchodilator response (BDR). OBJECTIVES: To examine whether stress and/or a gene regulating anxiety (ADCYAP1R1) is associated with BDR in PR and non-PR children with asthma. METHODS: This was a cross-sectional study of stress and BDR (percent change in FEV1 after BD) in 234 PRs ages 9-14 years with asthma. We assessed...
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