Article
Genomic Comparison Among Global Isolates of L. interrogans Serovars Copenhageni and Icterohaemorrhagiae Identified Natural Genetic Variation Caused by an Indel.
Frontiers in cellular and infection microbiology - 1 Jan 2018
Santos Luciane A, Adhikarla Haritha, Yan Xiting, Wang Zheng, Fouts Derrick E, Vinetz Joseph M, Alcantara Luiz C J, Hartskeerl Rudy A, Goris Marga G A, Picardeau Mathieu, Reis Mitermayer G, Townsend Jeffrey P, Zhao Hongyu, Ko Albert I, Wunder Elsio A
Abstract excerpt
Leptospirosis is a worldwide zoonosis, responsible for more than 1 million cases and 60,000 deaths every year. Among the 13 pathogenic species of the genus Leptospira, serovars belonging to L. interrogans serogroup Icterohaemorrhagiae are considered to be the most virulent strains, and responsible for majority of the reported severe cases. Serovars Copenhageni and Icterohaemorrhagiae are major representatives of...
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