Article
FAM83G/Fam83g genetic variants affect canine and murine hair formation.
Experimental dermatology - 1 Apr 2019
Balmer Pierre, Fellay Auxanne K, Sayar Beyza S, Hariton William V J, Wiener Dominique J, Galichet Arnaud, Müller Eliane J, Roosje Petra J
Abstract excerpt
FAM83G/Fam83g genetic variants have been described in dogs, mice and recently also in humans. They are associated with palmoplantar keratoderma and altered hair or coat phenotype, reported as wooly phenotype in mice. FAM83G/Fam83g is an unexplored effector of temporally and spatially coordinated Wnt and BMP signalling which are key pathways in pre- and postnatal hair follicle morphogenesis and differentiation....
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