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Article

Genetic polymorphisms of human transcription factor-7 like 2 (TCF7L2), β-defensin (DEFB1) and CD14 genes in nephrolithiasis patients.

International journal of biological macromolecules - 15 Oct 2018

Mehdi Wesen Adel, Mehde Atheer Awad, Raus Raha Ahmed, Yusof Faridah, Abidin Zaima Azira Zainal, Ghazali Hamid, Rahman Azlina Abd, Özacar Mahmut

Abstract excerpt

BACKGROUND: It is assumed that genetic factors play crucial role in nephrolithiasis. The present study was conducted to explore the role of Human Transcription Factor-7 like-2 (TCF7L2) β-defensin (DEFB1) and CD14 gene polymorphism in development and progression of nephrolithiasis. METHODS: The genotypes of TCF7L2, DEFB1 and CD14 polymorphism were determined in 240 nephrolithiasis patients and 240 healthy controls...

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beta-Defensins
DEFB1 gene
Gene Frequency
Genotype
Lipopolysaccharide Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nephrolithiasis

Polymorphism, Single Nucleotide

Transcription Factor 7-Like 2 Protein

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Identifiers

PMID: 29959006
DOI: 10.1016/j.ijbiomac.2018.06.113

Genes

DEFB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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