Article
Role of genetic mutations in development of immunological and clinical disorders in children with chronic pyelonephritis.
Wiadomosci lekarskie (Warsaw, Poland : 1960) - 1 Jan 2000
Harshman Vira P, Kryuchko Tetyana O, Kolenko Iryna O, Kushnereva Tetyana V, Tkachenko Olha Y
Abstract excerpt
INTRODUCTION: At the present time, the study of mechanisms of recognition of foreign agents, which is realized by means of Toll-like receptors (TLR) of the innate immune system, has become one of the main tasks of clinical immunology. The aim of our study was to investigate the prevalence of polymorphism of Toll-like receptor 4 (Asp299Gly, Gly299Gly) among children with chronic pyelonephritis (CP) and determine...
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