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Article

Association of MMP-9 gene polymorphisms with nephrolithiasis patients.

Journal of clinical laboratory analysis - 1 Jan 2018

Mehde Atheer Awad, Mehdi Wesen Adel, Yusof Faridah, Raus Raha Ahmed, Zainal Abidin Zaima Azira, Ghazali Hamid, Abd Rahman Azlina

Abstract excerpt

BACKGROUND: Nephrolithiasis is one of the causes which lead to chronic kidney disease (CKD). Matrix metalloproteinases (MMPs) are endopeptidases degrading extracellular matrix which correlate with the pathogenesis of atherosclerosis. The current study was designed to analyze the association of (R279Q, C1562T) polymorphism of MMP-9 with nephrolithiasis patients. METHODS: Genotyping of MMP-9/R279Q and of...

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PMID: 28205286
DOI: 10.1002/jcla.22173
PMCID: PMC6817110

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