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Identification of three novel loci of ALDH2 Gene for Serum Folate levels in a Male Chinese Population by Genome-Wide Association Study.

Gene - 20 Oct 2018

Deng Caiwang, Tang Shaomei, Huang Xiaoliang, Gao Jiamin, Tian Jiarong, Zhou Xianguo, Xie Yuanliang, Liao Ming, Mo Zengnan, Wang Qiuyan

Abstract excerpt

BACKGROUND: Serum folate is important in clinical researches and DNA synthesis and methylation. Some loci and genes that are associated with folate levels had been detected by genome-wide association studies (GWAS), such as rs1801133 in MTHFR and rs1979277 in SHMT1. Nevertheless, only a small part of variants has been clearly identified for serum folate. Hence, we conducted a GWAS to discover new inherited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase, Mitochondrial
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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 29953918
DOI: 10.1016/j.gene.2018.06.080

Genes

ALDH2
MTHFR
SHMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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