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Article

Identification of time-to-peak on dynamic 18F-FET-PET as a prognostic marker specifically in IDH1/2 mutant diffuse astrocytoma.

Neuro-oncology - 22 Jan 2018

Suchorska Bogdana, Giese Armin, Biczok Annamaria, Unterrainer Marcus, Weller Michael, Drexler Mark, Bartenstein Peter, Schüller Ulrich, Tonn Jörg-Christian, Albert Nathalie L

Abstract excerpt

Background: Stratification of glioma according to isocitrate dehydrogenase 1/2 (IDH1/2) mutation and 1p/19q codeletion status has gained major importance in the new World Health Organization (WHO) classification. Parameters derived from uptake dynamics of 18F-fluoro-ethyl-tyrosine PET (18F-FET-PET) such as minimal time-to-peak (TTPmin) allow discrimination between different prognostic glioma subgroups, too. The...

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Source

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Identifiers

PMID: 29016996
DOI: 10.1093/neuonc/nox153
PMCID: PMC5777500

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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