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Article

[Mutation Rate and Clinical Characteristics of CALR, JAK2 V617F and MPL W515K Genes in Patients With Primary Thrombocythemia].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2018

Yu Xiao-Wan, Huang Dong-Hong, Guo Jian-Xin, Huang Yue-Qin, Xie Ruo-Teng, Cai Jun-Feng

Abstract excerpt

OBJECTIVE: To analyze the mutation rate and clinical characteristics of CALR, MPL W515K and JAK2 V617F genes in patients with primary thrombocythemia (PT). METHODS: Fifty-six patients with PT were selected as the research objects in our hospital. The CALR and MPL W515K gene mutations were determined by genomic DNA-PCR direct sequencing of the PCR products, and the JAK2 V617F gene mutation was detected by allele...

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Source

Identifiers

PMID: 29950234
DOI: 10.7534/j.issn.1009-2137.2018.03.039

Genes

CALR
JAK2
MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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