Article
[Detection of ASXL1 Mutation and CALR Mutation Coexistance in Patients with Ph Negative Myeloproliferative Neoplasm and Its Clinical Gignificance].
Zhongguo shi yan xue ye xue za zhi - 1 Dec 2017
Chen Mei-Yu, Shen Hong-Jie, Chao Hong-Ying, Zhou Min, Lu Xu-Zhang, Zhang Xiu-Wen, Liu Jie, Jiang Nai-Ke, Wang Qian
Abstract excerpt
OBJECTIVE: To explore the coexistence of ASXL1 and CALR gene mutations in patients with essential thrombocytheima (ET) and with primary myelofibrosis(PMF), and to compare the differences of clinical characteristics between ET and PMF patients carrying ASXL1 and CALR mutations, and ET and PMF patients carrying solitary gene mutation, and ET and PMF patients without any mutations. METHODS: The mutations of ASXL1...
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