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Article

Circulating Interleukin-6 is Associated with Prognosis and Genetic Polymorphisms of MIR608 in Patients with Esophageal Squamous Cell Carcinoma.

Annals of surgical oncology - 1 Aug 2018

Yang Pei-Wen, Huang Pei-Ming, Yong Luo-Sheng, Chang Ya-Han, Wu Chia-Wei, Hua Kuo-Tai, Hsieh Min-Shu, Lee Jang-Ming

Abstract excerpt

BACKGROUND: No effective targeted therapy exists for esophageal squamous cell carcinoma (ESCC), the major cell type of esophageal cancer. The pleiotropic cytokine interleukin (IL)-6 is associated with adverse prognosis of some cancers, and the open reading frame of IL-6 contains an miR-608 microRNA-targeted site. We investigated the correlation of circulating IL-6 levels with prognosis and with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29948421
DOI: 10.1245/s10434-018-6532-4

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