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BRCAness Combined With a Family History of Cancer Is Associated With a Poor Prognosis for Breast Cancer Patients With a High Risk of BRCA Mutations.

Clinical breast cancer - 1 Oct 2018

Mori Hitomi, Kubo Makoto, Kai Masaya, Velasquez Vittoria Vanessa, Kurata Kanako, Yamada Mai, Okido Masayuki, Kuroki Syoji, Oda Yoshinao, Nakamura Masafumi

Abstract excerpt

BACKGROUND: The inexpensive prediction of the characteristics of BRCA-mutated breast cancer as "BRCAness" using the somatic cells of patients with breast cancer could be useful for developing a therapeutic strategy. Our objective was to correlate BRCAness with the clinicopathologic features, including a family history (FH) of cancer, in breast cancer patients with a high risk of BRCA mutations. PATIENTS AND...

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PMID: 29941390
DOI: 10.1016/j.clbc.2018.05.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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