Article
Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors.
Diabetes - 1 Aug 2018
Stamatouli Angeliki M, Quandt Zoe, Perdigoto Ana Luisa, Clark Pamela L, Kluger Harriet, Weiss Sarah A, Gettinger Scott, Sznol Mario, Young Arabella, Rushakoff Robert, Lee James, Bluestone Jeffrey A, Anderson Mark, Herold Kevan C
Abstract excerpt
Insulin-dependent diabetes may occur in patients with cancers who are treated with checkpoint inhibitors (CPIs). We reviewed cases occurring over a 6-year period at two academic institutions and identified 27 patients in whom this developed, or an incidence of 0.9%. The patients had a variety of solid-organ cancers, but all had received either anti-PD-1 or anti-PD-L1 antibodies. Diabetes presented with...
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