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Article

Clinical and HLA genotype analysis of immune checkpoint inhibitor-associated diabetes mellitus: a single-center case series from China.

Frontiers in immunology - 1 Jan 2023

Liu Yi-Chen, Liu Hong, Zhao Shao-Li, Chen Ke, Jin Ping

Abstract excerpt

Objective: To investigate the clinical characteristics and HLA genotypes of patients with immune checkpoint inhibitor-associated diabetes mellitus (ICI-DM) in China. Methods: We enrolled 23 patients with ICI-DM and 51 patients with type 1 diabetes (T1D). Clinical characteristics of the patients were collected. HLA-DRB1, HLA-DQA1, and HLA-DQB1 genotyping was conducted via next-generation sequencing. Results: The...

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Identifiers

PMID: 37359544
DOI: 10.3389/fimmu.2023.1164120
PMCID: PMC10288983

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