Article
Human Leukocyte Antigens and Biomarkers in Type 1 Diabetes Mellitus Induced by Immune-Checkpoint Inhibitors.
Endocrinology and metabolism (Seoul, Korea) - 1 Feb 2022
Inaba Hidefumi, Kaido Yosuke, Ito Saya, Hirobata Tomonao, Inoue Gen, Sugita Takakazu, Yamamoto Yuki, Jinnin Masatoshi, Kimura Hiroaki, Kobayashi Tomoko, Iwama Shintaro, Arima Hiroshi, Matsuoka Takaaki
Abstract excerpt
BACKGROUND: Type 1 diabetes mellitus induced by immune-checkpoint inhibitors (ICI-T1DM) is a rare critical entity. However, the etiology of ICI-T1DM remains unclear. METHODS: In order to elucidate risk factors for ICI-T1DM, we evaluated the clinical course and immunological status of patients with ICI-T1DM who had been diagnosed during 2016 to 2021. RESULTS: Seven of 871 (0.8%, six men and one woman) patients...
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