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Article

Tricarboxylic acid cycle without malate dehydrogenase in Streptomyces coelicolor M-145.

Archives of microbiology - 1 Nov 2018

Takahashi-Íñiguez Tóshiko, Barrios-Hernández Joana, Rodríguez-Maldonado Marion, Flores María Elena

Abstract excerpt

The oxidation of malate to oxaloacetate is catalysed only by a nicotinamide adenine dinucleotide-dependent malate dehydrogenase encoded by SCO4827 in Streptomyces coelicolor. A mutant lacking the malate dehydrogenase gene was isolated and no enzymatic activity was detected. As expected, the ∆mdh mutant was unable to grow on malate as the sole carbon source. However, the mutant grew less in minimal medium with...

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PMID: 29936645
DOI: 10.1007/s00203-018-1541-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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