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Article

Correlations of indoleamine 2,3-dioxygenase, interferon-λ3, and anti-HBs antibodies in hemodialysis patients.

Vaccine - 16 Jul 2018

Grzegorzewska Alicja E, Winnicka Hanna, Warchoł Wojciech, Mostowska Adrianna, Jagodziński Paweł P

Abstract excerpt

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) contributes to maintaining immune homeostasis. Polymorphisms (SNPs) of the IDO encoding gene (IDO1) influence the IDO activity. Interferon (IFN)-λ3 induces IDO expression. We aimed to investigate whether IDO1 variants are associated with anti-HBs production in response to HBV vaccination or infection, interact with IFN-λ3 associated variants of IFNL4, and influence...

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Identifiers

PMID: 29935858
DOI: 10.1016/j.vaccine.2018.06.034

Genes

IDO1

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