Article
Epigenetic machine learning: utilizing DNA methylation patterns to predict spastic cerebral palsy.
BMC bioinformatics - 21 Jun 2018
Crowgey Erin L, Marsh Adam G, Robinson Karyn G, Yeager Stephanie K, Akins Robert E
Abstract excerpt
BACKGROUND: Spastic cerebral palsy (CP) is a leading cause of physical disability. Most people with spastic CP are born with it, but early diagnosis is challenging, and no current biomarker platform readily identifies affected individuals. The aim of this study was to evaluate epigenetic profiles as biomarkers for spastic CP. A novel analysis pipeline was employed to assess DNA methylation patterns between...
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